Recombinant Human B7-1/CD80 Protein, His tag
产品名称： Recombinant Human B7-1/CD80 Protein, His tag
英文名称： Recombinant Human B7-1/CD80 Protein, His tag
产品编号： 93572ES25
产品价格： 655.00
产品产地： Yeasen
品牌商标： Yeasen
更新时间： 2025-02-06T16:45:15
使用范围： null
| 规格 | 价格 |
| 25ug | 655.0 |
| 100ug | 2625.0 |
| 500ug | 8775.0 |
| 1mg | 17545.0 |
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B7-1 is a member of the cell surface immunoglobulin superfamily. CD80 is mainly expressed on the surface of activated B cells, macrophages, dendritic cells and other antigen-presenting cells. B7-1 and B7-2 form co-stimulatory ligands that can interact with the co-stimulatory receptor CD28 expressed on T cells and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4). When interacting with CD28, it is generally used for self-regulation and intercellular binding; When interacting with CTLA-4, it is used to regulate attenuation and cell separation. CD80 plays a role in inducing congenital immune response by activating the NF-κb signaling pathway in macrophages. Therefore, CD80 is considered a promising therapeutic target for autoimmune diseases and various cancers.
性能参数
|
Synonyms |
CD80 molecule; B7; B71; B7-1; BB1; CD28LG1; CD80; B7.1; CD28LG1; LAB7 |
|
Uniprot No. |
P33681 |
|
Source |
Recombinant Human B7-1 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Val35-Asn242. |
|
Molecular Weight |
The protein has a predicted MW of 25.8 kDa. And it migrates as 33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
|
Purity |
> 95% as determined by SDS-PAGE. |
|
Endotoxin |
<0.1 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
|
Reconstitution |
Centrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 ug/mL. |
储存条件
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
注意事项
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.
产品数据
Ver. CN20230411