PDCD1 polyclonal antibody
产品名称： PDCD1 polyclonal antibody
英文名称： PDCD1 polyclonal antibody
产品编号： PAB13253
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PDCD1.
- Immunogen:
- A synthetic peptide corresponding to internal region 16 amino acids of human PDCD1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men.
Holling TM, Schooten E, van Den Elsen PJ.Hum Immunol. 2004 Apr;65(4):282-90.
- 2.
- Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor.
Nishimura H, Nose M, Hiai H, Minato N, Honjo T.Immunity. 1999 Aug;11(2):141-51.
- 3.
- Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
Ishida Y, Agata Y, Shibahara K, Honjo T.EMBO J. 1992 Nov;11(11):3887-95.
- Entrez GeneID:
- 5133
- Protein Accession#:
- Q15116
- Gene Name:
- PDCD1
- Gene Alias:
- CD279,PD1,SLEB2,hPD-1,hPD-l
- Gene Description:
- programmed cell death 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq
- Other Designations:
- -
- Related Disease
- Addison Disease
- Alveolitis, Extrinsic Allergic
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Carcinoma, Squamous Cell
- Choriocarcinoma
- Colitis, Ulcerative
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 1
- Disease Progression
- Disease Susceptibility
- Genetic Predisposition to Disease
- Graves Disease
- Hydatidiform Mole
- Inflammation
- Kidney Diseases
- Leukemia, chronic myeloid
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive